Line-up of PPAR agonists and antagonists,
which are nuclear receptors related to lipid- and sugar-metabolism!!!
Increase the product lineup sequentially.
PPAR（Peroxisome proliferator-activated receptor）, which is a nuclear receptor, is a transcription factor to regulate gene expression by forming hetero-dimer with RXR（Retinoid X receptor）and binding to promoter-region of target gene.
PPAR, is involved in lipid & sugar metabolism and cell proliferation & differentiation, is now attracting attention to the association between PPAR and diabetes, obesity & inflammation has been highly noted, lately.There are three subtypes: PPARα、PPARδ （PPARβ） and PPARγ.
PPARαAgonists: Bezafibrate; Clofibrate; Fenofibrate; WY-14643
PPARγ Agonists: Ciglitazone; Troglitazone
PPARγ Antagonists: GW9662