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Research for Alzheimer's Disease
BF-168 Senile plaque-selective fluorescent probe
BF-170 Neurofibrillary tangle change-selective fluorescent probe

 

Senile plaque staining with BF-168 and the Aβ immunostaining


BF-168, senile plaque-selective imaging probe is a usable reagent as well as the Immunostaining on Alzheimer's disease brain sections.

(Data was provided by Prof. Kudo Yukitsuka at Tohoku Univ. Biomedical Engineering Research Organization)


Staining of neurofibrillary change using BF-170 and the immunostaining


BF-170, neurofibrillary change-selective probe is a usable probe as well as the Immunostaining on Alzheimer's disease brain sections.

(Data was provided by Prof. Kudo Yukitsuka at Tohoku Univ. Biomedical Engineering Research Organization)



References
  1. Kitamoto, T.,Ogomori, K., Tateishi, J., and Prusiner, S. B.: Formic acid pretreatment enhances immunostaining of cerebral and systemic amyloids., Lab. Invest., 57, 230-236 (1987)
  2. Okamura, N., et al.: Styrylbenzoxazole derivatives for in vivo imaging of amyloid plaques in the brain, J. Neurosci., 24, 2535-2541 (2004)
  3. Okamura, N., Kudo, Y., et al.: Quinoline and benzimidazole derivatives: candidate probes for in vivo imaging of tau pathology in Alzheimer's disease., J. Neurosci., 25, 10857-10862 (2005)




Product List

Description
Wako Catalog No.
Package Size
BF-168
Senile plaque-selective fluoroescent probe
029-16361
1 mg
BF-170)
Neurofibrillary tangle change-selective fluorescent probe
026-16371
1 mg

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