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Cytokines involved in Th17 cell differentiation and maintenance
Interleukin-23

Interleukin-23 (IL-23) is a heterodimer protein comprising the p40 and p19 subunits of IL-23. IL-12 consists of heterodimer of the p40 and p35 subunits.  IL-23 and IL-12 are closely related to each other. IL-12 induces Th1 cell differentiation while IL-23 is involved in Th17 cell differentiation and maintenance.   IL-23 promotes secretion of inflammatory cytokines by stimulating memory CD4+ T cells. IL-23 is used in a variety of research including Crohn's disease, atopy, and cancer immunotherapy.

INDEX
  1. Product Overview
  2. Data
  3. Product List
  4. Related ProductS
  5. Links:   Wako's Cytokine List



1. Product Overview
  • Appearance: Solution (PBS + 0.1 w/v% BSA)
  • Origin: Sf+ cells expressed histidine tagged interleukin-23
  • Molecular weight: abt. 60 kDa for human IL
    abt. 65 kDa for mouse IL
  • Biological Activity: ED50 = ≤ 0.3 ng/mL
  • Endotoxin: ≤ 10 EU/mL
  • Concentration: 100 μg/mL
  • Purity (SDS-PAGE): ≥ 90% (before addition of BSA)

  • Storage Conditions: -80°C


2. Data
■ Human IL-23

«SDS-PAGE (1μg/mL)»
CBB Stain


«Biological activity test»
Biological activity measured by IL-17 induction in mouse spleen cells


■ Mouse IL-23

«SDS-PAGE (1μg/mL)»
CBB Stain


«Biological activity test»
Biological activity measured by IL-17 induction in mouse spleen cells


3. Product List
Product Name Grade Package Size Wako Catalog No. Storage Condition
Interleukin-23, Human, recombinant
(expressed in Insect Cells), Solution
for Cellbiology 10 μg 092-06441
Interleukin-23, Mouse, recombinant
(expressed in Insect Cells), Solution
for Cellbiology 10 μg 099-06451
QUOTATION REQUEST for IL-23, recombinant

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4. Related Products
Product Name Grade Package Size Wako Catalog No. Storage Condition
Interleukin-12, Human, recombinant for Cellbiology 10 μg 096-05361
Interleukin-12, Mouse, recombinant for Cellbiology 10 μg 095-05331
Interleukin-12 p40, Human, recombinant for Cellbiology 10 μg 095-05191
Interleukin-12 p40, Mouse, recombinant for Cellbiology 10 μg 098-05201


5. Link
⇒ Links to Wako's Cytokine List




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  • shows the storage condition should be at -20°C.
  • shows the storage condition should be at -80°C.

Home > Products > Life Science > Interleukin-23