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For the study of the feeling of cold sensor
TRPM8 related products

TRPM8(Transient Receptor Potential Melastatin8) is a known cold sensor, which has been considered to become active at below 25-28°C; however, a recent study has reported that the reaction temperature is depending on external temperature"



1. New Products

AMTB hydrochloride

AMTB HCl

AMTB is an antagonist of TRPM8(Transient Receptor Potential Melastatin8).

  • Appearance: white - thin yellowish brown, crystal - powder
  • DMSO clarity and color of solution: Examination conformity
  • assay(HPLC) : min 98.0%
  • C23H26N2O2S・HCl=430.99
  • CAS No.:926023-82-7
  • pIC50=6.231)

Icilin

Icilin

Icilin is an agonist of TRPM8 and TRPA1.

  • Appearance: thin yellowish brown - brown, crystalline powder - powder
  • DMSO clarity and color of solution: Examination conformity
  • assay(HPLC) : min 98.0%
  • C16H13N3O4=311.29
  • CAS No.:36945-98-9
  • EC50=0.2μmol/l2)

2. References

  1. Lashinger, E. S., Steiginga, M. S., Hieble, J. P., Leon, L. A., Gardner, S. D., Nagilla, R., Davenport, E. A., Hoffman, B. E., Laping, N. J. and Su, X. : Am. J. Physiol. Renal. Physiol., 295, F803 (2008).
  2. Behrendt, H. J., Germann, T., Gillen, C., Hatt, H. and Jostock, R. : Br. J. Pharmacol., 141, 737 (2004).

3. Product List

Product Name Package Size Wako Catalog No. Grade Storage Condition
AMTB Hydrochloride 5 mg 019-26191 for Cellbiology -
25 mg 015-26193
Icilin 10 mg 096-07181 Keep at -20°C.
50 mg 092-07183

4. Related Products

Product Name Product Name Wako Cat. No. Grade/Maker Storage Condition
TRPM8 agonists
l-Menthol

25 g

132-03752 Wako Special Grade -
100 g 134-03751
500 g 136-03755
TRPM8 antagonists
Anandamide

5 mg

018-25701 for Cellbiology Keep at -80°C.
25 mg 014-25703
2-APB

100 mg

013-24911 Keep at -20°C.
500 mg 019-24913
BCTC 10 mg 027-18241
50 mg 023-18243
Capsazepine 10 mg 037-23171
50 mg 033-23173

5. LINK

TRPA1 channel related reagents → Click here.

TRPV1 channel related reagents → Click here.

TRPV4 channel related reagents → Click here.

Home > Products > Life Science > Physiological Active Substances > TRPM8 related products
Home > Products > Life Science > Inhibitors > TRPM8 related products