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Reagents related to diabetic researches
α-glucosidase inhibitors

1. Acarbose
2. Miglitol
3. Voglibose
Product List


1. Acarbose
Acarbose delays absorption of carbohydrates by the inhibition of glucoamylase, sucrase and maltase in small intestinal brush-border membrane and α-amylase in pancreatic juice and saliva and, hence, inhibition of degradation of various carbohydrates except for monosaccharides in the gastrointestinal tract.
  • Assay (HPLC): 95.0+ %
  • CAS No.: 56180-94-0
  • C25H43NO18 = 645.60



  • 2. Miglitol
    Miglitol inhibits degradation from disaccharides to monosaccharides in the brush-border membrane of epithelial cells in small intestinal mucosa and delays digestion and absorption of carbohydrates. It exhibited inhibitory effects on sucrase and isomaltase derived from rat small intestines about 6 times and 120 times higher than those of acarbose.
  • Assay (HPLC): 97.0+ %
  • CAS No.: 72432-03-2
  • C8H17NO5 = 207.22



  • 3. Voglibose
    Voglibose inhibits α-glucosidase that degrades disaccharides to monosaccharides in the intestines and delays digestion and absorption of carbohydrates. It exhibited inhibitory effects on maltase and sucrase derived from porcine small intestines about 20 times and 30 times higher than those of acarbose and its inhibitory effects on maltase and sucrase derived from rat small intestines are about 270 and 190 times those of acarbose. On the other hand, voglibose does not exhibit inhibitory effect on β-glucosidase because its inhibitory effect on porcine and rat pancreatic α-amylase is about 1/3000 of that of acarbose.
  • Assay (HPLC): 100.0% (initial production lot)
  • CAS No.: 83480-29-9
  • C10H21NO7 = 267.28


  • Product List
    Product Name
    Package Size
    Wako Catalog No.
    Acarbose
    1 g
    019-22671
    10 g
    015-22673
    Miglitol
    10 mg
    138-16221
    100 mg
    134-16223
    1 g
    132-16224
    Voglibose
    2 mg
    220-01821
    10 mg
    226-01823
    100 mg
    224-01824
    Products listed in this page are for research use only.  Do not administer each to human.
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