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for Study of Nervous System Signals
Neurotransmitter Receptor Agonists / Antagonists

We offer a variety of neurotransmitter receptor agonists and antagonists.
This page introduces dopamine, serotonin, and cannabinoid agonists and antagonists. They will be useful in study of nervous system signals.

INDEX

  1. Dopamine Receptor Agonists/Antagonists
      ⇒  Clozapine
      ⇒ (+)-SCH23390 Hydrochloride
  2. Serotonin Receptor Agonists/Antagonists
      ⇒ Granisetron Hydrochloride
      ⇒ Ketanserin Tartrate
  3. Cannabinoid Receptor Agonists/Antagonists
      ⇒ AM630
      ⇒ WIN 55,212-2 Mesylate
      ⇒ Products Related to Cannabinoid Receptor Agonists/Antagonists



1. Dopamine Receptor Agonists / Antagonists

   ⇒ Clozapine

A dopamine D4 receptor-selective antagonist.

Also has an antagonistic effect against serotonin receptor 5-HT2A, 5-HT2C, 5-HT3, 5-HT6, and 5-HT7.

CAS No. 5786-21-0
Molecular formula/weight: C18H19ClN4 = 326.82
Assay: 98.0% (HPLC)

Product Name Grade Package Size Wako Catalog No.
Clozapine for Cellbiology 50 mg 037-21013

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     ⇒ (+)-SCH23390 Hydrochloride

A dopamine D1 receptor-selective antagonist and also serotonin 5-HT2C receptor agonist.

CAS No. 125941-87-9
Molecular formula/weight: C17H18ClNO・HCI= 324.24
Assay: 98.0+ % (HPLC)

Product Name Grade Package Size Wako Catalog No.
(+)-SCH23390 Hydrochloride for Cellbiology 10 mg 191-15531
50 mg 197-15533




2. Serotonin Receptor Agonists / Antagonists

  ⇒ Granisetron Hydrochloride

A serotonin 5-HT3 receptor-selective antagonist. Has an antiemetic effect.

CAS No. 107007-99-8
Molecular formula/weight: C18H24N4O・HCI= 348.87
Assay: 98.0+ % (HPLC)

Product Name Grade Package Size Wako Catalog No.
Granisetron Hydrochloride for Cellbiology 50 mg 078-25623

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   ⇒ Ketanserin Tartrate

A serotonin 5-HT2A receptor-selective antagonist.
Has a hypotensive effect in vivo. Also antagonizes vasoconstriction (induced by catecholamine and other vasoconstrictive substances) and platelet aggregation (induced by serotonin).

CAS No. 83846-83-7
Molecular formula/weight: C22H22FN3O3・H6O6 = 545.51
Assay: 97.0+ % (HPLC)

Product Name Grade Package Size Wako Catalog No.
Ketanserin Tartrate for Cellbiology 50 mg 119-00823



3. Cannabinoid Receptor Agonists / Antagonists

   ⇒ AM630

A CB2 cannabinoid receptor inverse agonist (Ki = 31.2 nM).

CB2 receptors are present in immune system organs such as the spleen and tonsil as well as in the peripheral nervous system and thought to control inflammation and immune responses.

CAS No. 164178-33-0
Molecular formula/weight: C23H25lN2O3 = 504.36
Assay: -

Product Name Grade Package Size Wako Catalog No.
AM630 for Cellbiology 2 mg 019-22551
10 mg 015-22553


   ⇒ WIN 55,212-2 Mesylate

A potent cannabinoid receptor agonist.

Cannabinoid receptors are thought to be associated with appetite, memory/learning, pain sensation, and immunity/inflammation.

CAS No. 131543-23-2
Molecular formula/weight: C27H26N2O3・CH3SO3H = 522.61
Assay: 97.0+ % (HPLC)

Product Name Grade Package Size Wako Catalog No.
WIN 55,212-2 Mesylate for Cellbiology 10 mg 238-02401
50 mg 234-02403
QUOTATION REQUEST for reagents for Steviol Glycosides
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   Products Related to Cannabinoid Receptor Agonists/Antagonists

Product Name Product Description Package Size Wako Catalog No.
(-)-CP-55,940 A potent non-selective cannabinoid receptor agonist.
Ki= human recombinant CB1 receptor: 0.58 nM, human recombinant receptor CB2: 0.69 nM
2 mg 038-20781
10 mg 034-20783
JWH015 A CB2 cannabinoid receptor-selective agonist.
Ki= human recombinant CB2 receptor: 13.8 nM, human recombinant receptor CB1: 383 nM
5 mg 102-00111
25 mg 108-00113
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Note

  • Listed products are intended for laboratory research use only, and not to be used for drug, food or human.
  • Please visit our online catalog to search for other products from Wako: http://www.e-reagent.com
  • This information may contain products that cannot be exported to your country due to regulations.
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