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Research for Alzheimer's Disease
Memantine Hydrochloride

Memantine hydrochloride is a glutamate NMDA receptor antagonist. It shows neuroprotective effects and improves memory and learning by limiting excessive NMDA receptor activation by glutamate. It is a new promising compound for the treatment of Alzheimer's dementia.

INDEX
  1. Summary of Product Characteristics
  2. Product List
  3. Related Products
  4. Reference
  5. Link to Neurobiochemistry brochure



1. Summary of Product Characteristics






  • Assay (cGC): 100.0% (the first production lot)
  • Solubility: Soluble in water (1 mg/mL)
  • C12H21N·HCl = 215.76
  • IC50: 1.2 ± 0.2 μmol/L 1)
  • 2. Product List
    Product Name Grade Package Size Wako Catalog No. Storage Condition
    Memantine Hydrochloride for Cellbiology 25 mg 132-16981 Room Temperature
    100 mg 138-16983
    QUOTATION REQUEST for IL-23, recombinant

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    3. Related Products
    ■ Amyloid Proteins
    Product Name Grade Package Size Wako Catalog No. Storage Condition
    Amyloid β-Protein (1-40) (Hydrochloride) for Biochemistry 1 mg 014-18951
    Amyloid β-Protein (1-42) (Hydrochloride) for Biochemistry 1 mg 011-18961
    Amyloid β-Protein (25-35) for Biochemistry 1 mg 017-20031

    ■ β-Secretase Inhibitors suitable to in vivo Research
    ⇒ <LINK> to Neurobiochemistry brochure
    Product Name Grade Package Size Wako Catalog No. Storage Condition
    KMI-429 for Cellbiology 1mg 115-00901
    KMI-574 for Cellbiology 1 mg 112-00911
    KMI-1027 for Cellbiology 1 mg 119-00921
    KMI-1303 for Cellbiology 1 mg 116-00931


    Selective Fluorescent Probes for Senile Plaque · Neurofibrillary Tangle
    ⇒ <LINK> to Neurobiochemistry brochure
    Product Name Grade Package Size Wako Catalog No. Storage Condition
    BF-168 for Cellbiology 1 mg 029-16361
    BF-168 for Cellbiology 1 mg 026-16371


    ■ βAmyloid Immunohistostain Kit
    Product Name Package Size Wako Catalog No. Storage Condition
    Amyloid beta-Protein Immunohistostain Kit 50 tests 299-56701 Keep at 2~10°C



    ELISA Kits for β Amyloid determination <for Immunochemistry>
    ⇒ <LINK> to Neurobiochemistry brochure
    Product Name Package Size Wako Catalog No. Storage Condition
    Human β Amyloid(1-40) ELISA Kit Wako 96 tests 292-62301 Keep at 2~10°C
    Human β Amyloid (1-40) ELISA Kit Wako II 96 tests 298-64601
    Human β Amyloid (1-42) ELISA Kit Wako 96 tests 298-62401
    Human β Amyloid (1-42) ELISA Kit Wako, High Sensitive 96 tests 296-64401
    Human/Rat β Amyloid (40) ELISA Kit Wako 96 tests 294-62501
    Human/Rat β Amyloid (40) ELISA Kit Wako II 96 tests 294-64701
    Human/Rat β Amyloid (42) ELISA Kit Wako 96 tests 290-62601
    Human/Rat β Amyloid (42) ELISA Kit Wako, High Sensitive 96 tests 292-64501
    *Thiese kits are not for in vitro diagnostic use.

    4. Reference
    1. Chen H.-S. V. and Lipton S. A.: Mechanism of memantine block of NMDA-activated channels in rat retinal ganglion cells: uncompetitive antagonism, J. Physiol.,499.1, 27-46 (1997)

    5. Link
    ⇒ Links to Neurobiochemistry and Neurological Diseases




    Note
    • Listed products are intended for laboratory research use only, and not to be used for drug, food or human.
    • Please visit our online catalog to search for other products from Wako: http://www.e-reagent.com
    • This information may contain products that cannot be exported to your country due to regulations.
    • Bulk quote requests for some products are welcomed. Please contact us or our distributor near you.
    • shows the storage condition should be at -20°C.

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