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Home > Products > Life Science > Immunochemistry > 4.1G, Mak, ICK, Trβ2 polyclonal antibodies

Polyclonal antibodies for optic nerve research
4.1G, Mak, ICK, Trβ2 polyclonal antibodies

Polyclonal antibodies to factors involved in the development and function of optic nerves


1. Features

  • Performances of each antibody has been demonstrated within KO mice.
  • Applications are available.

2. Antibody Information

  Anti Mouse 4.1G / EPB41L2, Rabbit Anti Mouse ICK, Guinea Pig Anti Mouse Mak, Guinea Pig Anti Mouse Trβ2, Rabbit
Wako
Cat. No.
018-26421 015-26431 012-26441 016-24261
Package Insert
Antigen Synthetic peptide
TPRLRKRGKDPSENRGIC
(57-73 a.a.) of 4.1G/EPB41L2
Synthetic peptide corresponding to 346-412 a.a. of ICK His-tagged C-terminal sequence (296-622 a.a.) of mouse Mak Recombinant mouse Trβ2 N-terminal fragment (1-107 a.a.)
Antigen
factor
information
4.1G (Alias: EPB41L2) is one of the ERM family proteins with a molecular weight about 113 kDa. It preserves the formation of cytoplasmic membranve. Recently, it is reported to regulate synaptic location in the retina and normal visuality by using KO mouse. It is also used as a rod cell marker. ICK (Alias: MRK, LCK2) is a kinase protein with a molecular weight about 71 kDa. It localizes at the tip of cilia regulating cliliary transport. ICK phosphorylates Kif3a and essential for proper cliliogenesis. Mak (Alias: DJ417M14.2) is a kinase protein with a molecular weight of 71 kDa. It regulates ciliary length by phosphorylating RP1. Trβ2 (Thyroid hormone receptor beta 2) is a high affinity receptor for triiodothyronine.
Trβ2 is required for the development of green cone photoreceptors of embryonic retina. It is also used as a cone cell marker.
Host / Isotype Rabbit / IgG Guinea pig / IgG Guinea pig / IgG Rabbit / IgG
Species cross reactivity mouse
(Other species have not been tested)
mouse
(Other species have not been tested)
mouse
(Other species have not been tested)
mouse
(Other species have not been tested)
Applications ■Immunocytochemistry
 1 : 5,000 - 10,000
■Western Blot
 1 : 10,000 - 100,000
■Immunocytochemistry
 1 : 100
■Western Blot
 1 : 250
■Immunocytochemistry
 1 : 1,000
■Western Blot
 1 : 3,000
■Immunocytochemistry
 1 : 1,000
■Western Blot
 1 : 1,000
Application
data
(Immuno-cytochemistry)

Green:4.1G/EPB41L2
■Sample: mouse retina

Red:ICK
■Sample: mouse embronic fibroblast


Green:Mak Red:γ-tubulin
■Sample: mouse retina


Green:Trβ2
■Sample: mouse retina
References Sanuki, R., et al.: Cell Reports, 10, 796 (2015). Chaya, T., et al.: The EMBO Journal, 33,1227 (2014). Omori, Y., et al.: Proc. Natl. Acad. Sci. 107, 22671 (2010). Sanuki, R., et al.: Nature Neurosci., 14, 1125 (2011).

Data was provided by Takahisa Furukawa, Laboratory for Molecular and Developmental Biology, Institute for Protein Research, Osaka University.

3. Product List

Wako Cat. No. Product Name Pkg. Size Grade Storage Condition
018-26421 Anti Mouse 4.1G/EPB41L2, Rabbit 50 μL for Immunochemistry Keep at -20°C.
015-26431 Anti Mouse ICK, Guinea Pig 50 μL
012-26441 Anti Mouse Mak, Guinea Pig 50 μL
016-24261 Anti Mouse Trβ2, Rabbit 50 μg

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* Clicking on a product code will link to the Wako Online Catalog "www.e-reagent.com, where you can check the current price and stock status of the product.

Home > Products > Life Science > Immunochemistry > 4.1G, Mak, ICK, Trβ2 polyclonal antibodies